Lesions of the Hypothalamic Paraventricular Nucleus and Norepinephrine Turnover in Rats.
نویسندگان
چکیده
منابع مشابه
Increased Cyclooxygenase-2 Expression in Hypothalamic Paraventricular Nucleus in Rats
We investigated the role of nuclear factor B (NFB) in the cytokine-mediated induction of cyclooxygenase-2 activity in the paraventricular nucleus of hypothalamus (PVN), a critical cardiovascular and autonomic center, in rats with heart failure (HF). Sprague–Dawley rats underwent coronary artery ligation to induce HF or sham surgery. HF rats were treated orally for 6 weeks with vehicle (tap wate...
متن کاملHigh NaCl diet reduces hypothalamic norepinephrine turnover in hypertensive rats.
The current study tested the hypothesis that high NaCl diets elevate blood pressure in NaCl-sensitive spontaneously hypertensive rats (SHR-S) by reducing noradrenergic input to depressor neurons in the anterior hypothalamus. SHR-S were studied at 7 weeks of age, and age-matched salt resistant SHR (SHR-R) and normotensive Wistar-Kyoto rats (WKY) were controls. Rats were fed either high (8%) NaCl...
متن کاملPRL-releasing peptide inhibits food intake in male rats via the dorsomedial hypothalamic nucleus and not the paraventricular hypothalamic nucleus.
PRL-releasing peptide inhibits food intake after intracerebroventricular injection. PRL-releasing peptide immunoreactivity is found in several hypothalamic nuclei involved in feeding, with highest levels in the paraventricular and dorsomedial hypothalamic nuclei. The aim of this study was to examine the effect of PRL-releasing peptide on food intake after administration into these nuclei. Parav...
متن کاملHypothalamic Paraventricular Nucleus Modulates Sympathetic Excitation
Aldosterone stimulates the sympathetic nervous system by binding to a select population of brain mineralocorticoid receptors (MR). These MR have an equal affinity for corticosterone that is present in substantially higher concentrations, but are held in reserve for aldosterone by activity of the enzyme 11 -hydroxysteroid dehydrogenase type 2 (11 -HSD-2), which converts corticosterone to an inac...
متن کاملAltered GABAA α5 subunit expression in the hypothalamic paraventricular nucleus of hypertensive and pregnant rats
A characteristic of both hypertension and pregnancy is increased sympathetic nerve activity. The level of sympathetic activation is determined, in part, by a tonic GABAergic inhibition arising from the hypothalamic paraventricular nucleus (PVN). In hypertension, decreases in GABAergic inhibition and increases in glutamatergic excitation within the PVN contribute to this sympatho-excitation. In ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1989
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.36.187